Research faculty at the University of Maryland School of Pharmacy are nationally and internationally renowned for their work in the fields of pharmaceutical sciences and health outcomes research.
Pharmaceutical Sciences (PSC)
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Andrew Coop, PhD Professor of Pharmaceutical Sciences Associate Dean for Graduate Programs Research Interests: Synthesis of morphine (opioids) analogs and biochemical studies of the mechanisms of cocaine and methamphetamine (stimulants) attenuation -- towards developing new treatments for drug addiction |
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Richard Dalby, PhD Professor of Pharmaceutical Sciences Research Interests: Optimization of drug delivery to the lung and nose to understand what factors affect the performance of pressurized metered dose inhalers, dry powdered inhalers, nebulizers, and nasal sprays |
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Daniel J. Deredge, PhD Assistant Professor of Pharmaceutical Sciences Research Interests: Application of mass spectrometry-based biophysical approaches, with a particular focus on Hydrogen-Deuterium exchange, integrated with computational approaches for the structural and biophysical characterization of proteins within the context of protein structure and dynamics, protein/macromolecules interaction and protein/ligands interactions |
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Natalie D. Eddington, PhD, FAAPS, FCP Professor of Pharmaceutical Sciences Research Interests: Nationally known expert in drug delivery and pharmacokinetics, with research focused on cancer therapy and treatments for disorders of the central nervous system |
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Steven Fletcher, PhD Associate Professor of Pharmaceutical Sciences Director, MS in Pharmaceutical Sciences Research Interests: Rational design of drugs towards new treatments for cancer and inflammation, discovery of traditional small-molecules, harnessing covalent chemistries to accomplish sustained inhibitions of target proteins, as well as leveraging proteolysis-targeting chimera and molecular glue technologies to achieve the targeted degradation of disease-causing proteins |
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Stephen Hoag, PhD Professor of Pharmaceutical Sciences Research Interests: Development of systematic methods for formulating controlled and immediate release tablets, and the use of mathematical models to understand the mass transport processes in hydrogels |
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Chad Johnson, PhD Research Interests: Synthesis of novel, fast-acting antidepressants targeting the muscarinic receptors (mAChRs) for major depressive disorder and opioid analgesics with reduced reinforcement for treatment of drug addiction. |
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Jace W. Jones, PhD Associate Professor of Pharmaceutical Sciences Research Interests: Development of innovative mass spectrometry based platforms to probe the structure/function dynamics of lipids. Research covers analytical instrumentation, application to model systems, and bioinformatic integration of multidimensional datasets. |
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Maureen Kane, PhD Professor of Pharmaceutical Sciences Director, Mass Spectrometry Center Research Interests: Development of new bio-analytical technologies for quantitative profiling of metabolites and proteins; elucidating the role of retinoid binding and retinoid metabolism in cancer, diabetes, obesity, and inflammation |
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Berhanu Kibret, PhD Research Interests: Role of the endocannabinoid system (ECS) in neuropsychiatric and neurodegenerative disorders with a nuanced emphasis on unraveling the intricate involvement of neuronal and glial type 2 cannabinoid (CB2) receptors in neuroimmune and behavioral effects. |
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Alexander MacKerell, PhD Grollman-Glick Professor of Pharmaceutical Sciences Research Interests: Structure-function relationships of proteins, carbohydrates, and nucleic acids; computer-aided drug design targeting cancer, opioids, immunosuppression, and other diseases; the development of empirical force fields for biological and pharmaceutical compounds |
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Sarah L.J. Michel, PhD Dean, University of Maryland School of Pharmacy Professor of Pharmaceutical Sciences Research Interests: Investigation of metalloregulatory proteins that recognize and regulate DNA and RNA, and participate in inflammation, cancer, normal neuronal development, and immune response |
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Amanda Oglesby, PhD Professor of Pharmaceutical Sciences Director, PhD in Pharmaceutical Sciences Research Interests: Investigations into iron-responsive small regulatory RNAs (sRNAs) in bacterial pathogens using a combination of genetics, proteomics, metabolomics, in vitro phenotypic analyses, in vivo infection models, and various expression analysis tools to determine how sRNAs are expressed, identify their cellular targets, and characterize their role in pathogenesis |
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Ryan M. Pearson, PhD Associate Professor of Pharmaceutical Sciences Research Interests: Developing strategies for treating dysregulated immune responses in areas such as allergy, inflammation, infectious disease, and cancer through the merger of two enabling disciplines, nanotechnology and immune engineering. |
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James Polli, PhD Professor of Pharmaceutical Sciences Ralph F. Shangraw/Noxell Endowed Chair in Industrial Pharmacy and Pharmaceutics Director, MS and Graduate Certificate in Regulatory Science Research Interests: Studies on the inclusion of bioavailability considerations in drug design and the pharmacokinetic evaluation of oral solid dosage forms |
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C.S. Raman, PhD Associate Professor of Pharmaceutical Sciences Research Interests: Multifaceted structural and biological studies that combine high-resolution X-ray crystallography with biochemistry, biophysics, molecular biology, and evolutionary and phylogenetic analyses |
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Paul Shapiro, PhD Professor of Pharmaceutical Sciences Associate Dean for Research Research Interests: Mechanistic studies of mitogen-activated protein (MAP) kinase signaling pathways and regulation of cancer cell proliferation and inflammation with the goal of discovering novel function-selective MAP kinase inhibitors that specifically block signaling events that drive the pathology of disease but have fewer off-target effects in normal tissue |
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Jana Shen, PhD Professor of Pharmaceutical Sciences Research Interests: Development of molecular simulation and data science tools for drug and materials design; mechanisms of opioid receptors and ion/substrate transporters; reversible and covalent drug design targeting kinases and proteases |
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Yan Shu, PhD Professor of Pharmaceutical Sciences Research Interests: Investigation of drug transport mechanisms and metabolism in therapeutics, particularly how different factors such as genetic polymorphisms and diseases affect drug transporters, metabolizing enzymes, and, therefore, drug responses |
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Audra Stinchcomb, PhD Professor of Pharmaceutical Sciences Research Interests: Investigation of the mechanisms and optimization of prodrug skin permeation and microneedle-enhanced skin permeation, as well as the influence of prodrug physicochemical properties on skin flux, distribution, and metabolism |
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Marc Taraban, PhD Associate Research Professor of Pharmaceutical Sciences Research Interests: Dynamic nuclear magnetic resonance (NMR) applications in low and high field to study solvent-solute interactions; water relaxation rate as a probe for noninvasive characterization of biopharmaceuticals; and applications of modern biophysical and structural biology methods, such as DLS, MFI, SAX(N)S, etc., to study structural characteristics and conformational dynamics in biopolymers, molecular assemblies, and dendrimers |
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Hongbing Wang, PhD Professor and Interim Chair, Pharmaceutical Sciences Program Chair, Experimental and Translational Therapeutics Research Interests: Investigations of the molecular mechanisms that govern the xenobiotic-induced regulation of metabolizing enzymes and drug transporters in humans, including metabolism-associated drug-drug interactions, drug-induced liver toxicity, and interaction between pharmacogenomics and nuclear receptor-mediated induction of drug-metabolizing enzymes |
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Angela Wilks, PhD Research Interests: Addressing the question of how bacterial pathogens acquire and utilize heme as an iron source in survival and virulence has led to the design of patented inhibitors of heme utilization as novel antimicrobials. Utilizing a systems biology approach, this research combines bacterial genetics, metabolomics, biochemical and biophysical tools |
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Patrick Wintrode, PhD Associate Professor of Pharmaceutical Sciences Research Interests: Characterization of pathological protein conformations using biophysical techniques to elucidate how these contribute to disease; mass spectrometry and computer simulations are also being used to determine how the molecular dynamics of HIV proteins contribute to drug susceptibility and drug resistance |
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Fengtian Xue, PhD Associate Professor of Pharmaceutical Sciences Research Interests: Investigation of the mechanism and biological functions of disease-related enzymes using novel cellular imaging agents, as well as rational design, synthesis, and biological evaluation of potential medicinal agents for human diseases such as traumatic brain injury, neurodegeneration, and cancer |
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Bruce Yu, PhD Professor of Pharmaceutical Sciences Research Interests: Biomaterials engineering research to investigate the link between molecular chirality and material mechanical properties, and research in the area of imaging technologies towards developing imaging agents for multicolor F-19 MRI |
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Wenbo Yu, PhD Research Assistant Professor of Pharmaceutical Sciences Research Interests: Computer-aided drug design (CADD) targeting cancer and other diseases; new CADD methods development and coding; force field development; and molecular level simulation for phenomenon of biological and medicinal interests |
Practice, Sciences, and Health Outcomes Research (P-SHOR)
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Wendy Camelo Castillo, MD, PhD, MSc Assistant Professor of Practice, Sciences, and Health Outcomes Research Director, Pharmaceutical Health Services Research Graduate Program Research Interests: Pharmacoepidemiology; development and implementation of methods for comparative effectiveness and patient centered outcomes research; health disparities |
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Peter Doshi, PhD Associate Professor of Practice, Sciences, and Health Outcomes Research Research Interests: Credible evidence synthesis; evidence-based medicine; reporting biases; drug safety; drug regulation; medical journalism; evidence, policy, and advocacy in public health |
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Susan DosReis, PhD Professor of Practice, Sciences, and Health Outcomes Research Co-Vice Chair for Research and Scholarship Research Interests: Pharmacoepidemiology; pediatric mental health behavioral science |
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Allison Dunn, PharmD, MS Research Interests: Clinical pharmacology; the applications of pharmacometrics in both clinical practice and clinical development |
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Joga Gobburu, PhD Professor of Practice, Sciences, and Health Outcomes Research Director, Center for Translational Medicine Research Interests: Pediatrics; clinical pharmacology and translational research; comparative effectiveness; pharmacometrics |
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Mathangi Gopalakrishnan, PhD, MS Associate Professor of Practice, Sciences, and Health Outcomes Research Research Interests: Pharmacometrics, Bayesian applications in drug development, and innovative clinical trial designs |
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C. Daniel Mullins, PhD Professor of Practice, Sciences, and Health Outcomes Research Executive Director, The PATIENTS Program Research Interests: Pharmacoeconomics; comparative effectiveness research and health disparities |
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Eberechukwu Onukwugha, PhD, MS Professor of Practice, Sciences, and Health Outcomes Research Research Interests: Pharmacoeconomics, healthcare resource utilization, and health disparities. |
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Eleanor Perfetto, PhD, MS Professor of Practice, Sciences, and Health Outcomes Research Research Interests: Health policy issues, including issues related to comparative effectiveness research, health care quality performance measurement, patient-focused drug development, and reimbursement |
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Danya Qato, PhD, PharmD, MPH Associate Professor of Practice, Sciences, and Health Outcomes Research Research Interests: Improving regulatory and policy tools to reduce use of high risk medications in vulnerable populations; risk management and post-marketing surveillance; environmental and global health systems development; pharmacovigilance; and health disparities |
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Fadia Shaya, PhD, MPH Professor of Practice, Sciences, and Health Outcomes Research Distinguished University Professor Executive Director, Behavioral Health Resources Program Director of Informatics and Implementation Research, Institute for Clinical and Translational Research Research Interests: Pharmacoeconomics; pharmacoepidemiology; health policy and regulatory science; comparative effectiveness of drugs and medical devices; disparities and social determinants of health; entrepreneurship |
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Julia Slejko, PhD Associate Professor of Practice, Sciences, and Health Outcomes Research Research Interests: Medication adherence and decision-analytic modeling for cost effectiveness and comparative effectiveness research |
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Ester Villalonga Olives, PhD, MsC Associate Professor of Practice, Sciences, and Health Outcomes Research Research Interests: Patient reported outcomes; social epidemiology; and health inequalities |
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Linda Wastila, PhD, MSPH, BSPharm Professor and Parke-Davis Chair in Geriatric Pharmacotherapy Research Interests: Health services research in mental health and substance use disorders in geriatrics |
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Zafar Zafari, PhD, MSc Associate Professor of Practice, Sciences, and Health Outcomes Research Research Interests: Mathematical/statistical simulation modeling; cost-effectiveness analyses; statistical methods of prediction; Bayesian methods for evidence synthesis; optimal resource allocation based on personalized clinical data; and health policy |