The NMR Facility at the University of Maryland School of Pharmacy features two state-of-the-art spectrometers.

500 MHz NMR Spectrometer:

This spectrometer is located in the basement of Health Sciences Facility II (HSF II), and is equipped with:

Hardware:

  • Agilent DD2
  • 4-channels
  • 5mm pentaprobe/Z pulsed field gradient
  • 5mm HFCN probe/Z pulsed field gradient
  • Variable temperature (-20 to 80 degrees Celsius)

Software:

  • Linux-based operating system Red Hat 5.3
  • VNMRJ 4.2

Primary uses for this instrument include:

  • 1D: H1; C13; N15; F19; P31
  • 2D: COSY; TOCSY; HSQC; HMBC; ROESY; NOESY
  • 3D: Standard proton detect experiments for labeled protein, including HNCA, HNCO, HNCACB
  • Diffusion spectroscopy

400 MHz NMR Spectrometer:

This spectrometer is located in the basement of Health Sciences Facility II (HSF II), and is equipped with:

Hardware:

  • Varian 400 MR Direct Drive console
  • 2-channels
  • 5mm broad band probe/Z pulsed field gradient

Software:

  • Dell host computer Red Hat 5.3
  • VNMRJ 3.0

Primary uses for this instrument include:

  • 1D: H1; C13; N15; F19; P31; tunable to other nuclei
  • 2D: Basic experiments, including COSY; TOCSY; HSQC; HMBC; ROESY; NOESY