Technologies and Patents

Research conducted in the Bio- and Nano-Technology Center (BNTC) at the University of Maryland School of Pharmacy has led to patents for several new, innovative technologies.

Technologies for characterizing biopharmaceuticals, nanomedicines, and biomaterials.

Biomaterial Characterization
- Patent: Noninvasive characterization of mechanical properties of materials and issues using magnetic resonance techniques (US9348008, Issued on May 24, 2016).

Therapeutic Protein Characterization
- Patent: Assessing Biopharmaceutical Aggregation Using Magnetic Resonance Relaxometry (US10267754, Issued on April 23, 2019)
- Patent: Biopharmaceutical Aggregation Assessment and Counterfeit Detection Using Magnetic Resonance Relaxometry (US10514374, Issued on Dec. 24, 2019)
- Patent: Biopharmaceutical Aggregation Assessment and Counterfeit Detection Using Magnetic Resonance Relaxometry (US10724974, Issued on July 28, 2020)
- Patent: Biopharmaceutical Aggregation Assessment and Counterfeit Detection Using Magnetic Resonance Relaxometry (EU patent No. 2984482, issued on September 9, 2020)
- Patent: Targeted Structure-Specific Particulate Delivery Systems (EU3220900, Issued on Sept. 23, 2020)

Technologies for making biopharmaceuticals, nanomedicines, and biomaterials.

Defect-free Dendrimer Synthesis
Patent: Dendrimers and methods of preparing same through proportionate branching (US9133114, Issued on Sept. 15, 2015).

Highly Fluorinated β-amino Acids
Patent: Highly fluorinated β-amino acids and methods of making and using same (US8052961, Issued on Nov. 8, 2011).

Highly Fluorinated Oils and Surfactants
Patent: Highly fluorinated oils and surfactants and methods of making and using same (US8252778 B2, Issued on Aug. 28, 2012).

Hydrogel Construction
Patent: Electrostatically controlled hydrogels (US9364412, Issued on June 14, 2016).

Compositions and methods for delivering nucleic acids to cells.
Pearson, R. M., Chakraborty, A., (United States Patent Application Number: PCT/US2020/055272. 2020).