Postdoctoral Fellowships

Postdoc position on protein formulation development and characterization of protein excipients interactions to correlate with computational methods.

Location: University of Maryland Baltimore, Baltimore, MD

When: As soon as possible

Funding support: NIH grants

Minimal requirements: Candidates must have PhD or equivalent degree/experience and
working permit in the US.

Description: Drs. Daniel Deredge and Stephen Hoag are hiring 2 post-docs for a joint project on the development and characterization of protein formulations; in particular, we will be examining the role excipients play in the chemical and physical stability of various biological proteins and IgG antibodies

The first postdoc will work with Dr. Hoag and will be developing formulations for various biologic proteins and IgG antibodies using different excipients and processing techniques; this will be followed by stress testing these formulations to see how excipients affect formulation physical and chemical stability. Candidates who have knowledge or excipients, protein formulation and process development are encouraged to apply.

The second postdoc will work with Dr. Deredge and be responsible with characterizing the effect of these formulations and excipients on the structure and dynamics of the biologic protein and IgG antibodies using hydrogen-deuterium exchange coupled with mass spectrometry (HDXMS). Candidates with prior experience in bottom up HDX-MS are highly encouraged to apply.

A successful candidate must have a knowledge of protein formulation and characterization,
excellent analytical skills, be able to design experiments, analyze data, write up results and work as a team with each other and with computational collaborators. For a highly motivated candidate without prior experience we would be willing to train in certain areas.

Please send your CV, along with contacts of three references to Dr. Stephen Hoag
(shoag@rx.umaryland.edu) and Dr. Daniel Deredge (dderedge@rx.umaryland.edu).

Postdoctoral positions are available at the University of Maryland, Baltimore. The positions
are located at the Shady Grove Campus, Institute for Bioscience and Biotechnology Research located in Rockville, Maryland / IBBR. IBBR is a joint research institute between the University Maryland and the National Institute of Standards and Technology (NIST). IBBR is in close proximity to multiple pharma/biotech companies as well the FDA, NIH and USP. The trainees will work closely with researchers from the University of Maryland and NIST. There are also opportunities to work with scientists from industry. The projects apply biophysical techniques to characterize biologics, such as vaccines, therapeutic proteins and gene therapy products. Candidates should have a Ph.D. in biophysics, biochemistry, physical chemistry or related fields. Background in NMR spectroscopy is highly desirable. Send applications to Prof. Bruce Yu at byu@rx.umaryland.edu.

Please visit the Mass Spectrometry page for the most up to date job postings. 

Location: University of Maryland Baltimore, Baltimore, MD

Description: Post-doctoral position is available starting February 2021 in the Department of Practice, Sciences, and Health Outcomes Research at the University of Maryland School of Pharmacy. The position provides a multidisciplinary research and training environment in collaborations with local and state policy makers, and prepares fellows for positions in academia, pharmaceutical or insurance industries, consulting, and government. The position will be primarily for one year with possible extension.

The select candidate will engage in health policy and health economic modeling research with activities funded by Maryland Department of Transportation (MDOT), foundations, FDA, and private corporations. Training includes mentored research and grant-writing. This position involves working closely with academic scholars, policy makers, and other stakeholder partners. 

Qualifications: Doctoral level degree in Health Economics, Health Policy, Epidemiology,
Economics, Operations Research, Health Services Research or related analytical field is required. Prior research experience in health economic modeling, systematic reviews and meta-analysis, cost-effectiveness analysis, and health policy is desired. Knowledge of statistical programming in SAS, R, or Python is required. Excellent communication, organizational, and time management skills are a must.

How to Apply: Applicants should submit a letter of interest, curriculum vita, writing sample,
and three letters of recommendation. Review of applications will start immediately. 

To apply or to receive more information, please contact Dr. Zafar Zafari and send applications to: zzafari@rx.umaryland.edu

Zafar Zafari, MSc, PhD
Assistant Professor
University of Maryland School of Pharmacy